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Abstracts & Commentary

Colorectal Cancer Risk Reduction Using Metformin

By Davis W. Lamson, ND
Last month we learned of metformin’s anticancer benefits in breast cancer. This month we review the evidence for its potential to prevent colorectal cancer. And again we ask, “What place does metformin have in natural medicine?”

Acetaminophen and Risk of Behavioral Problems in Children

By Michael T. Murray, ND, and Karolyn A. Gazella
Associations between prenatal use of acetaminophen and behavioral problems in children adds to concerns about the safety of what is widely considered to be a benign over-the-counter remedy for pain and fever.

Benefits of Elderberry for Symptoms of Common Cold in Air Travelers

By Michael Traub, ND, DHANP, FABNO
In this placebo-controlled study, elderberry extract reduced symptoms and duration of common colds related to air travel, but the quality of the study raises some concerns.

Peer-Reviewed Articles

A Hydrolyzed Casein Standardized to Lactotripeptides for Support of Vascular Health

By Ginny Bank, MS
Lactotripeptides (LTPs) found in fermented milk have been shown to have potential antihypertensive properties by acting as angiotensin-converting enzyme (ACE) inhibitors. A standardized LTP product, with levels of LTP higher than what is available from dairy products, has also been shown in both in vitro and animal models to induce nitric oxide (NO) production and attenuate atherosclerosis. Clinical research has confirmed that LTP can promote vasodilation, improve endothelial function, and mitigate arterial stiffness in prehypertensive and hypertensive subjects. In this review of published research on the standardized LTP product, we discuss its established mechanisms of action and the randomized placebo-controlled clinical trials that document its potential beneficial effects on cardiovascular health.

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