Abstracts & Commentary
With 1 in 3 Americans having high blood pressure, antihypertensive drugs are among the most frequently prescribed medicines in America. There are 11 different antihypertensive drug classes to choose from, each with its own risks and side effects. For those requiring a medication for control, this study suggests there may be an associated risk of breast cancer in postmenopausal women taking calcium channel blockers for a long duration.
Nut consumption was associated with a significantly reduced risk of all-cause mortality. Compared to non-consumers, subjects consuming nuts >3 servings/week had a 39% lower mortality risk. A similar protective effect against cardiovascular and cancer mortality was observed.
The theory that estrogen metabolite ratios are predictive of cancer risk is failing in these studies to be predictive. This current paper is one more in a series that call this hypothesis into question. It may be time for our profession to reassess the theory and rethink the clinical practices we have adopted based on these assumptions.
We now know that minute quantities of reactive oxygen species are essential to life, and that high levels are detrimental. The concept that nutrients also have doses that are beneficial, beyond which they are detrimental, is in keeping with the idea that optimal physiological function is a balance within the cells and the organism as a whole.
The current standard of care does not include detection of asymptomatic atherosclerosis. Instead, traditional risk factors are evaluated, the patient is put into a low-, medium-, or high-risk category, and lipid targets are determined by the clinician depending on the category. Thus, coronary artery disease is not detected early. We know that early detection of cancer saves lives. The same is true for atherosclerosis.
Interviews with Experts
As a companion piece to our Q&A with M Mamadou, PhD, in the September 2013 NMJ Supplement, we asked Dr Mamadou to outline some specific digestive orders that can benefit from the use of supplemental digestive enzymes.