Abstracts & Commentary
Ten patients undergoing "fecal bacteriotherapy," or what in the United States is often termed "fecal transplantation." In this process the bowel is cleansed with antibiotics and then fecal suspensions from healthy donors are administered daily.
Forty-two men, aged 45 to 70 years (mean age 63 (SD 5.5) years), participated in this study. All subjects entering the study had lower urinary tract symptoms (LUTS), elevated PSA and/or BHP (BPH). Other inclusion criteria were histological findings of acute or chronic non-bacterial prostatitis, normal urinary sediment and negative bacterial cultivation of urine. The diagnosis was asymptomatic inflammatory prostatitis category IV according to the National Institute of Health classification system.
Colicky infants taking L. reuteri experienced a significant decrease in daily crying time. Stool microbiology revealed an increase in lactobacilli and decrease in Escherichia coli in the treatment group. L. reuteri was well tolerated and no adverse effects were noted.
Multicenter, randomized, double-blinded, placebo-controlled phase III trial. Three hundred seventy-nine patients with unresectable stage III non-small cell lung cancer (NSCLC) were enrolled between June 5, 2000, and February 6, 2006. All patients received chemotherapy, including a platinum-based agent, and radiotherapy. Patients were randomly assigned in a 1:1 ratio to receive either 120 ml of AE-941 (Neovastat) (n=188) or an equal dose of placebo (n=191) orally twice daily.
This open label study included 60 type 2 diabetes mellitus patients divided into 3 groups; 18 patients received sesame oil, 20 patients took a daily dose of glibenclamide (Glyburide), and 22 took both sesame oil and glibenclamide. The patients in the sesame group were supplied with sesame oil and instructed to use about 35 grams (about 2.4 tablespoons) per day in cooking or salad preparation for 60 days. Blood samples were collected at baseline and after 60 days of the experiment for analysis.
Cisplatin use is limited by severe neurotoxicity. When the cumulative dose exceeds 300 mg/m2, in some reports most patients suffer significant neurological damage. Cisplatin is known to increase oxidative stress; vitamin E is an antioxidant, and current evidence suggests that the antioxidant actions of vitamin E do not interfere with the therapeutic effect of chemotherapy.
Controlled clinical trial to evaluate the effect of oral magnesium therapy on ocular blood flow and visual field perimetry indices in patients with normotensive glaucoma (NTG). Blood magnesium level measurement, visual field analysis, and color Doppler imaging of the orbital vessels were done before treatment and at 1 month.
Trained interviewers questioned 390 subjects (209 men, 181 women) a median of 3 days after acute ischemic stroke. Each subject's coffee consumption in the hour before stroke symptoms appeared was compared with his or her usual frequency of consumption in the prior year.
Randomized controlled trial of 162 patients with various cancers. Average age was 60 years old (range 31-86) All patients had a prognosis >12 months and had never done QiGong before participating in the study. Outcome measures, including quality of life (QOL), fatigue, mood, and an inflammatory biomarker were measured before intervention and at 10 weeks post-intervention.
Data was collected on 201 patients 10 to 18 years of age, referred to the pediatric hypertension clinic at the University of Rochester Medical Center over a 3-year period. Subjects were assessed as either having or not having primary hypertension. Patients were considered hypertensive if either systolic or diastolic measurements were above the 95th percentile at the initial visit with subsequent confirmation by 24-hour ambulatory blood pressure monitoring, assessment by a school nurse, or home monitoring. Provider-confirmed learning disabilities (LDs) and/or formal treatment for attention deficit/hyperactivity disorder (ADHD) were assessed per parent report.
