March 2011 Vol. 3 Issue 3

Abstracts & Commentary

Shark Cartilage Fails to Benefit Lung Cancer Patients

by Tina Kaczor, ND, FABNO  Multicenter, randomized, double-blinded, placebo-controlled phase III trial. Three hundred seventy-nine patients with unresectable stage III non-small cell lung cancer (NSCLC) were enrolled between June 5, 2000, and February 6, 2006. All patients received chemotherapy, including a platinum-based agent, and radiotherapy. Patients were randomly assigned in a 1:1 ratio to receive either 120 ml of AE-941 (Neovastat) (n=188) or an equal dose of placebo (n=191) orally twice daily.

Magnesium Citrate Improves Vision in Normotensive Glaucoma

by Michael T. Murray, ND  Controlled clinical trial to evaluate the effect of oral magnesium therapy on ocular blood flow and visual field perimetry indices in patients with normotensive glaucoma (NTG). Blood magnesium level measurement, visual field analysis, and color Doppler imaging of the orbital vessels were done before treatment and at 1 month.

Vitamin E Protects Patients from Cisplatin-induced Neuropathy in a Randomized Trial

by Steve Austin, ND  Cisplatin use is limited by severe neurotoxicity. When the cumulative dose exceeds 300 mg/m2, in some reports most patients suffer significant neurological damage. Cisplatin is known to increase oxidative stress; vitamin E is an antioxidant, and current evidence suggests that the antioxidant actions of vitamin E do not interfere with the therapeutic effect of chemotherapy.

Sesame Oil and Diabetes

by Jacob Schor, ND, FABNO  This open label study included 60 type 2 diabetes mellitus patients divided into 3 groups; 18 patients received sesame oil, 20 patients took a daily dose of glibenclamide (Glyburide), and 22 took both sesame oil and glibenclamide. The patients in the sesame group were supplied with sesame oil and instructed to use about 35 grams (about 2.4 tablespoons) per day in cooking or salad preparation for 60 days. Blood samples were collected at baseline and after 60 days of the experiment for analysis.

Association of Oral Magnesium with Type-2 Diabetes

by Carolyn Dean, MD, ND  Magnesium intake by the study population was inadequate and a high percentage of individuals presented alterations in the status of this mineral.

Peer-Reviewed Articles

Lycopene's Effects on Health and Diseases

by V. Kalai Selvan, MPharm, PhD  Lycopene is present in many fruits and vegetables, with tomatoes and processed tomato products being among the richest sources. This review highlights the scientific documentation of lycopene as a therapeutic agent. Lycopene may alleviate chronic diseases such as cancer and coronary heart disease. Lycopene has also been found effective in the treatment of eye diseases, male infertility, inflammation, and osteoporosis. Experimental, clinical, and epidemiological studies have also established its role in the management of diabetes and hepatoprotection.


Lise Alschuler, ND, FABNO, Addresses the Issue of Absorption of Oral Glutathione Supplementation

by Natural Medicine Journal In this new audio series offered by <i>Natural Medicine Journal</i>, Lise Alschuler, ND, FABNO, discusses why she values glutathione in her clinical practice and clarifies issues associated with oral absorption of this important antioxidant.

Quality Standards

The Winding, Global Path of Dietary Supplements

by Lise Alschuler, ND, FABNO  One of the pleasures of winter in New England is its revelation of the wonder of my dog's nose. During our walks at any other time of year, with her nose pressed to the ground, it appears as if my dog is enthusiastically, albeit randomly, on the hunt for something she hasn't found yet. However, in the winter, those apparently random sniffs are transformed before my eyes into a precise tracing of an animal's trail. With the help of tracks left in the snow, I can now see the trail that my dog's nose is leading her along. It amazes me how accurate she is in staying on the trail, and I know that, with enough time, she could easily follow the trail all the way to its source.

Book Reviews

Book Review: Amy Rothenberg's New Collection of Essays

by Jacob Schor, ND, FABNO  Back in 1991 when Amy Rothenberg's husband Paul Herscu first book was published, it came as a shock. Rothenberg and Herscu had only graduated National College of Natural Medicine in 1986. With barely four years of clinical experience they had produced a volume, The Homeopathic Treatment of Children, that quickly become a foundation text for all of us. Even now, after 20 years in practice, I still read it regularly and marvel at the depth of the their knowledge.