by Jacob Schor, ND, FABNO
The mitochondrial free radical theory of aging is currently one of the more widely accepted theories to explain the aging process. It posits that aging results from free radical damage to mitochondrial DNA that is caused by reactive oxygen species (ROS) generated within the mitochondria during complex I electron transport. Vulnerability to ROS peroxidation, and thus aging, varies with the quantity of polyunsaturated fatty acids incorporated into cellular membranes. The current data in support of this theory suggest that antioxidant intake has little impact on increasing maximal longevity and also that intake of polyunsaturated fatty acids may be associated with faster aging. These implications are relevant to clinical practice.
by Kimberly Sanders, ND
Lack of association between dietary soluble fiber intake and islet cell autoimmunity leads to questions about the role of diet-related gut microbiome alterations and their influence on immunomodulation.