February 13, 2018

Why the Dangers are Mounting over BPA

Sponsored by the Environmental Health Symposium

Learn more at the Environmental Health Symposium

April 6-8, 2018 in Scottsdale, AZ


Bisphenol A (BPA) is a ubiquitous environmental contaminant, primarily metabolized by glucuronidation that is associated with various human diseases. It is a high throughput chemical-over 6 billion pounds are produced globally each year. While there is a huge market and multiple industrial uses for this compound, its deleterious effect on human health continues to be revealed. BPA has demonstrated adverse effects on human beings being currently exposed, but its epigenetic effects on fetal development and for several generations after, are just now beginning to be explored.

BPA has been shown to be an endocrine disruptor, reproductive toxin, and have neurodevelopmental and epigenetic effects including an increased risk of breast and prostate malignancies. Ingestion of BPA is thought to undergo rapid glucuronidation with a short half-life measured in hours. However, due to the ubiquitous exposure to BPA, the NHANES data has shown BPA is present in 93% of Americans.

Additionally, studies have shown that the β-glucuronidase present in placental tissue attenuates this rapid clearance of BPA. Indeed, in one human study it was shown that urine BPA levels in pregnant women increased 25% over pre-pregnancy levels, thus exposing the fetus to higher levels. Studies have also suggested that the fetus itself has reduced ability to detoxify BPA due to limited hepatic mRNA and protein expression of 13 UGT genes including UGT 2B15, highly involved in glucuronidation of BPA, which were not detectable in the fetus and were reduced in children compared to adults.

While some regulatory work has been successful in prohibiting BPA in baby items, BPA and its regrettable substitutions are still widely available. It would behoove all practitioners to carefully advise and guide avoidance with their patients while the toxicokinetics and epigenetic effects of BPA continue to unfold.

BPA may be the most potent low-level obesogen and diabesogen in your patients’ bodies. Dr. Todd Hagobian will be presenting his research showing how to effectively address BPA exposure at the Environmental Health Symposium 2018, April 6-8, in Scottsdale, AZ. There is no intervention that lowers BPA more effectively than avoidance. Handouts and resources will be given for immediate implementation. Learn more and register here

EHS Co-chair Lyn Patrick, ND interviews Dr. Todd Hagobian on Facebook.

Blog written by best selling author, Anne Marie Fine, NMD, who will be presenting on The Avoidance of Everyday Exposures at this year’s conference.

Environmental Health Symposium April 6-8, 2018 “Reducing Toxic Load” in Scottsdale, AZ

The Environmental Health Symposium is the premier Environmental Medicine conference dedicated to helping clinicians become proficient and current in diagnosing and treating patients whose illness stems from a burden of toxic compounds. This conference provides strategies to prevent and reverse the conditions that are threatening the health and vitality of this and future generations to come.

This year’s conference theme, Reducing Toxic Load, focuses on those vulnerable to toxic exposures while providing evidence for reducing toxic load. The CDC reports that over 120 toxic chemicals and metals, out of a total of 246 measured, are present in the average US resident. Attendees will learn effective strategies that safely lower body burden and improve health outcomes; gain expertise in evaluating body burden of toxicants from experts in the field of Environmental Medicine; discover the newest research and the most useful laboratory testing in the field of toxicogenomics and how to apply this knowledge in helping individual patients; become an expert in the application of nutrition and botanical strategies for reducing body burden and avoidance of everyday toxicants in your patients and yourself.

Come to EHS and join the growing community of healthcare providers committed to offering answers to the increasing number of patients with conditions related to toxic environmental exposures.

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