Peer-Reviewed Articles
New clinical applications for the alkaloid berberine have come to light in recent years. Applications related to adenosine monophosphate-activated protein kinase (AMPK) activation and berberine's possible therapeutic use in metabolic syndrome, type 2 diabetes, and dyslipdemia are reviewed in this article. Potential applications related to cancer are not discussed here but are reserved for a second review.
Parkinson's disease (PD) is a neurodegenerative disorder marked by resting tremors, rigidity of movement, postural abnormalities, and akinesia. The "trigger"for the onset of PD is not known and is presumed to be multifactorial, involving genetic susceptibility and environmental agents.
Healthcare providers can help prevent and treat osteoporosis by supporting the improvement of nutritional status through diet and nutritional supplementation, along with suggestion for an increase in exercise training.
Some research has raised concern that parabens may be associated breast cancer. Parabens have
been detected in human breast tissue and have shown estrogenic properties.
There is a need for more extensive research into the development of the immune system in infants so that we have a more
complete understanding of how to target and prevent immune disorders. Our current understanding points to 4 main areas in
the ontogeny of the infant's immune system as potential early intervention points for the prevention of immune disorders.
Conventional therapies have limited success in preventing or reversing symptoms of neuropathic pain and numbness. In the past decade there has been a surge in publications suggesting acetyl-L-carnitine (ALC) may be an effective neuroprotectant and antinociceptive for peripheral neuropathy. This review highlights the uses, doses, and proposed mechanisms of action for the therapeutic effects of ALC in patients with peripheral neuropathy.
It is certainly possible, as these papers suggest, to significantly lower the formation of carcinogens during cooking, even while barbecuing. Incorporating specific ingredients into meat through mixing, marinades, or rubs provides accessible means to inhibit formation of HCAs.
Vitamin B6 (pyridoxine) is required for the synthesis of the neurotransmitters serotonin and norepinephrine and for myelin formation. This monograph summarizes the research on the vitamin, including information on its most and least effective uses.
Vitamin D is one of the most publicized nutrients today. This monograph assesses the recent research, outlines the most and least promising uses for the vitamin, and explains interactions and contraindications.
Cherries, the fruit of Prunus cerasus trees, and their juice concentrates may be clinically beneficial in various conditions, including gout, arthritis, muscle injury, diabetes and neurodegeneration. In general tart cherries contain more beneficial phytochemicals.
