Peer Reviewed Articles

Recommending Intermittent Fasting

by Ronald Hoffman, MD
For health and longevity, the timing of when we eat and when we fast profoundly affects our physiology.

Highlighting Alpha Lipoic Acid in Diabetes

by Tina Kaczor, ND, FABNO
Alpha lipoic acid (ALA), given orally or intravenously, affects many conditions in which oxidation and inflammation are involved. One of the conditions for which exogenous ALA has been most studied is diabetes. Understanding ALA’s structure and use as an exogenous agent that is more akin to a drug than a nutrient, with particular attention to diabetes and diabetic peripheral neuropathy, is the topic of this review.

An Updated Review on Hormone Replacement Therapy for Menopausal Women

by Timothy Schwaiger, ND
Menopause can be a challenge for women who suffer from unwanted symptoms including insomnia associated with night sweats and hot flashes, vaginal dryness, and chronic urinary problems. In addition, for those contemplating hormone replacement therapy (HRT) while evaluating its use and the potential for aggravating side effects and medical risks, the information available to the public can be confusing.

Beneficial Effects of a Sulfur-Containing Supplement on Hair and Nail Condition

by Neelam Muizzuddin, PhD
Significant changes were observed in as little as 2 weeks of dietary supplementation.

Diet and Risk of Prostate Cancer Recurrence

by Jacob Schor, ND, FABNO
This peer-reviewed paper presents a comprehensive review of the latest evidence to support specific dietary recommendations for men with prostate cancer. Data suggests there is no one-size-fits-all solution; recommendations for prevention may differ from those for reducing risk of progression or recurrence, and there may even be inter-individual variation.

Demographic and Outcome Trends in Naturopathic Teaching Clinics

by Kimberly Sanders, ND
A pilot study explores individualized naturopathic care and health-related quality of life in 2 demographically distinct clinic populations.

Arum palaestinum as a Food-Medicine

by Benton Bramwell, ND
Commonly known as Solomon’s lily, Arum palaestinum is an edible, flowering plant that has been used in Traditional Arabic Palestinian herbal medicine for millennia, both as food and as treatment for a wide variety of ailments. A literature review of both in vitro and in vivo studies sheds light on its potential as an anticancer treatment for modern times.

Oncology Acupuncture Program Assessment at Oregon Health and Science University

by Yiyi Chen, PhD
A retrospective analysis aims to create a profile of cancer patients who opt to receive acupuncture for treatment-related symptoms, to inform symptom assessment and shed light on acupuncture efficacy in this subpopulation.

Thiamine Deficiency and Diabetic Polyneuropathy

by Richard H. Mann, DPM
An exploration of the complex metabolic pathways that connect thiamine deficiency to complications of diabetes.

Let’s Talk About Sex: Sexuality During and After Cancer Treatment

by Judith Boice, ND, LAc, FABNO
Cancer and cancer treatments present special challenges that can affect sexuality and sexual desire. A review article thoughtfully addresses this overlooked aspect of patient care and provides practical suggestions for enhancing intimacy.

The Gut-Skin Axis and Mechanisms for Communication

by Raja Sivamani, MD
The association of gut health to general health has been the focus of many medical approaches, including traditional Chinese medicine, Ayurvedic medicine, and naturopathic medicine. The discovery of the gut microbiome has led to new areas of research that focus on the possible biochemical mechanisms that can relate gut health to local disease as well as the health of distant organs. The relationship of the gut to the skin, referred to as the gut-skin axis, is one emerging area of research.

Testosterone Deficiency Diagnosis and Replacement Therapy

by Timothy Schwaiger, ND
The use of testosterone replacement therapy (TRT) for men has risen dramatically in recent years. This comprehensive review article covers many aspects of TRT, including testosterone metabolism, indications for TRT, diagnostic testing with a decision-to-treat algorithm, contraindications, and risks vs benefits of treatment.

Beyond Brain Damage

by Jill Crista, ND
A fascinating review article describes in detail the many downstream effects of endocrine damage caused by traumatic brain injury, effects that manifest themselves in symptoms that may not be recognized as a consequence of brain trauma.

The Uses of Low-Dose Naltrexone in Clinical Practice

by Timothy Schwaiger, ND
Naltrexone is known as a treatment for opioid addiction, but studies suggest naltrexone taken in lower doses may yield benefits for other health issues. This review article discusses potential applications of low-dose naltrexone and presents mechanisms of action that could explain its beneficial effects.

The Human Microbiome in Cancer

by Tina Kaczor, ND, FABNO
Our understanding of the human microbiome continues to mushroom. A review of recent research reveals the influence of dysbiosis on cancer and cancer treatment outcomes.

Current Controversy: Does Adrenal Fatigue Exist?

by Sarah Bedell Cook, ND
What’s in a name? Controversy over “adrenal fatigue” diagnosis may have more to do with terminology than physiology.

Health Effects of Anger in Men

by Steve Rissman, PhD
A fascinating review article provides convincing evidence that anger negatively affects many aspects of men’s health in addition to its more well-recognized cardiovascular effects, making a case for the value of addressing anger issues in our male patients.

Mediterranean Diet for Cancer Prevention

by Michelle Qaqundah, ND, FABNO
The benefits of a Mediterranean diet have been touted for years, but evidence of its health-promoting effects continues to mount. This article reviews more recent studies that underscore the diet’s cancer-preventing effects, and provides an in-depth analysis of the diet itself, including specific suggestions for food selection and preparation to improve adherence.

Management of Recurrent Pregnancy Loss

by Jaclyn Chasse, ND
The loss of a single pregnancy can be devastating, but some women experience multiple losses, compounding the devastation. Dr. Chasse explains many potential causes of pregnancy loss and provides guidelines for evaluation and treatment, noting that naturopathic clinicians have much to offer.

Perioperative Probiotics in Abdominal Surgeries

by Rebecca Lovejoy, ND, LAc
The use of probiotics to support general health is widespread, and quite a bit of research has been conducted on the use of various strains and doses in various contexts. Based on available research, some guidelines have been developed on clinical use of beneficial bacteria under specific disease or treatment circumstances, regarding strains, doses, and expected outcomes. This article highlights available evidence related to the use of probiotics in abdominal surgery as an addition to standard perioperative procedures, such as prophylactic antibiotic administration, with special attention to the use of probiotics in the perioperative gastrointestinal (GI) oncology setting, a narrow focus that lies beyond the scope of current guidelines.