Peer Reviewed Articles

Oncology Acupuncture Program Assessment at Oregon Health and Science University

by Yiyi Chen, PhD
11-07-2018 
A retrospective analysis aims to create a profile of cancer patients who opt to receive acupuncture for treatment-related symptoms, to inform symptom assessment and shed light on acupuncture efficacy in this subpopulation.

Thiamine Deficiency and Diabetic Polyneuropathy

by Richard H. Mann, DPM
11-07-2018 
An exploration of the complex metabolic pathways that connect thiamine deficiency to complications of diabetes.

Let’s Talk About Sex: Sexuality During and After Cancer Treatment

by Judith Boice, ND, LAc, FABNO
10-24-2018 
Cancer and cancer treatments present special challenges that can affect sexuality and sexual desire. A review article thoughtfully addresses this overlooked aspect of patient care and provides practical suggestions for enhancing intimacy.

The Gut-Skin Axis and Mechanisms for Communication

by Raja Sivamani, MD
08-15-2018 
The association of gut health to general health has been the focus of many medical approaches, including traditional Chinese medicine, Ayurvedic medicine, and naturopathic medicine. The discovery of the gut microbiome has led to new areas of research that focus on the possible biochemical mechanisms that can relate gut health to local disease as well as the health of distant organs. The relationship of the gut to the skin, referred to as the gut-skin axis, is one emerging area of research.

Testosterone Deficiency Diagnosis and Replacement Therapy

by Timothy Schwaiger, ND
08-01-2018 
The use of testosterone replacement therapy (TRT) for men has risen dramatically in recent years. This comprehensive review article covers many aspects of TRT, including testosterone metabolism, indications for TRT, diagnostic testing with a decision-to-treat algorithm, contraindications, and risks vs benefits of treatment.

Beyond Brain Damage

by Jill Crista, ND
05-16-2018 
A fascinating review article describes in detail the many downstream effects of endocrine damage caused by traumatic brain injury, effects that manifest themselves in symptoms that may not be recognized as a consequence of brain trauma.

The Uses of Low-Dose Naltrexone in Clinical Practice

by Timothy Schwaiger, ND
04-04-2018 
Naltrexone is known as a treatment for opioid addiction, but studies suggest naltrexone taken in lower doses may yield benefits for other health issues. This review article discusses potential applications of low-dose naltrexone and presents mechanisms of action that could explain its beneficial effects.

The Human Microbiome in Cancer

by Tina Kaczor, ND, FABNO
11-15-2017 
Our understanding of the human microbiome continues to mushroom. A review of recent research reveals the influence of dysbiosis on cancer and cancer treatment outcomes.

Current Controversy: Does Adrenal Fatigue Exist?

by Sarah Bedell Cook, ND
10-04-2017 
What’s in a name? Controversy over “adrenal fatigue” diagnosis may have more to do with terminology than physiology.

Health Effects of Anger in Men

by Steve Rissman, PhD
08-23-2017 
A fascinating review article provides convincing evidence that anger negatively affects many aspects of men’s health in addition to its more well-recognized cardiovascular effects, making a case for the value of addressing anger issues in our male patients.

Mediterranean Diet for Cancer Prevention

by Michelle Qaqundah, ND, FABNO
05-03-2017 
The benefits of a Mediterranean diet have been touted for years, but evidence of its health-promoting effects continues to mount. This article reviews more recent studies that underscore the diet’s cancer-preventing effects, and provides an in-depth analysis of the diet itself, including specific suggestions for food selection and preparation to improve adherence.

Management of Recurrent Pregnancy Loss

by Jaclyn Chasse, ND
04-19-2017 
The loss of a single pregnancy can be devastating, but some women experience multiple losses, compounding the devastation. Dr. Chasse explains many potential causes of pregnancy loss and provides guidelines for evaluation and treatment, noting that naturopathic clinicians have much to offer.

Perioperative Probiotics in Abdominal Surgeries

by Rebecca Lovejoy, ND, LAc
04-05-2017 
The use of probiotics to support general health is widespread, and quite a bit of research has been conducted on the use of various strains and doses in various contexts. Based on available research, some guidelines have been developed on clinical use of beneficial bacteria under specific disease or treatment circumstances, regarding strains, doses, and expected outcomes. This article highlights available evidence related to the use of probiotics in abdominal surgery as an addition to standard perioperative procedures, such as prophylactic antibiotic administration, with special attention to the use of probiotics in the perioperative gastrointestinal (GI) oncology setting, a narrow focus that lies beyond the scope of current guidelines.

Ideal Dosing: The Sweet Spot of Natural Medicine

by Jacob Schor, ND, FABNO
03-01-2017 
Although we instinctively understand that you can have too much of a good thing, sometimes our approach to natural remedies is to assume if a little bit helps, more is better. This analysis introduces principles related to optimal dosing and reviews recent literature.

Recognizing Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants (ASIA)

by Tina Kaczor, ND, FABNO
02-01-2017 
Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants (ASIA) is a relatively new entity introduced in 2011. Diagnosis of ASIA is based on major and minor criteria encompassing generalized signs and symptoms such as persistent fatigue, cognitive difficulties, neurological deficits, myalgias/arthralgias, and dry mouth. As the name implies, an immune adjuvant is requisite, although the adjuvant itself may or may not be identified. ASIA is thought to be a rare entity, which makes the identification and study of those affected challenging. Knowledge of ASIA may help clinicians identify patients with underlying immune dysregulation.

A Hydrolyzed Casein Standardized to Lactotripeptides for Support of Vascular Health

by Ginny Bank, MS
12-07-2016 
Lactotripeptides (LTPs) found in fermented milk have been shown to have potential antihypertensive properties by acting as angiotensin-converting enzyme (ACE) inhibitors. A standardized LTP product, with levels of LTP higher than what is available from dairy products, has also been shown in both in vitro and animal models to induce nitric oxide (NO) production and attenuate atherosclerosis. Clinical research has confirmed that LTP can promote vasodilation, improve endothelial function, and mitigate arterial stiffness in prehypertensive and hypertensive subjects. In this review of published research on the standardized LTP product, we discuss its established mechanisms of action and the randomized placebo-controlled clinical trials that document its potential beneficial effects on cardiovascular health.

Lifestyle Interventions Enhance Quality of Life and Reduce Recurrence Risk Among Cancer Survivors

by Lise Alschuler, ND, FABNO
11-02-2016 
There are 15.5 million cancer survivors in the United States and, according to the American Cancer Society, this number is projected to increase to 20 million by 2026. In recognition of the unique health needs of this growing population, the American College of Surgeons Commission on Cancer has mandated that cancer centers provide survivors with a Survivorship Care Plan. This review provides scientific substantiation regarding key lifestyle intervention strategies that both help cancer centers meet the mandate, and help cancer survivors heal from treatment, reduce their risk of cancer recurrence, and enhance overall wellness.

The Immune System: An Integrative Perspective

by Eric Secor
10-26-2016 
A healthy and intact immune response requires coordination between skin, mucosal barriers, and both the innate and adaptive aspects of immune response. With an overarching mandate of protection, the blueprints of individual immune surveillance systems are inherited through family history and fashioned through interactions with the environment, including lifestyle choices and chemical exposures. The goal of this article is to provide an overview of the immune response and opportunities for assessment, treatment, and management from an integrative medical perspective.

Biodiversity, Nature, and Human Health

by Kristen Arvidson
10-05-2016 
Some recent studies claim biodiversity has a positive effect on human health, whereas human alterations to the natural environment have unfavorable health effects. This brief literature review cites current research that endorses biodiversity for human health and examines the negative consequences of natural environment modification. The review focuses on the health benefits of biodiverse environments, outdoor activity, and plant interactions, as well as the negative health effects of human disturbances, climate change, and urban landscapes.

Asthma’s Perfect Storm

by Matthew Baral, ND
09-21-2016 
Asthma affects approximately 24 million Americans, and 6.3 million of those are under 18 years of age. The reliance on asthma medication as the only treatment for this widespread condition has had virtually no effect on asthma rates, which have continually increased since the 1980s. It is therefore imperative that the medical community at large start to commit to prevention as an equally important measure when considering asthma as a condition. A holistic perspective should take into account all the factors affecting asthma prevalence and expose the connections between them.