Peer Reviewed Articles
06-01-2012 Diminished ovarian reserve, a natural process by which the follicular pool diminishes with time, is often clinically asymptomatic but presents a challenge to those wanting to become pregnant. Although pelvic ultrasonography and day 3 serum hormone testing have long been common methods of assessing ovarian reserve, there is promising research to suggest the utility of anti-Mullerian hormone testing to identify patients with diminished ovarian reserve.
05-01-2012 Long-term use of oral contraceptives (OCs) and of hormone replacement therapy (HRT) have been linked to increased blood coagulation, with its increased risk of cardiovascular problems. Their long-term use also has been linked to altered immune and inflammatory factors, suggesting an increased risk of chronic immune disorders with an inflammatory component, including cancer. This report reviews these various risks.
04-01-2012 The incidence of colorectal cancer is highest in Western populations. It is thought that the reason for this is largely modifiable lifestyle factors. Primary care practitioners are uniquely positioned to influence the habits of their patients. Screening and early diagnosis have profound effects on the prognosis of individuals with colorectal cancer, and recognizing those at high risk may save lives through early detection. In addition, many evidence-based nutritional interventions exist that may reduce the risk of developing colorectal cancer in those at high risk.
03-01-2012 Siberian ginseng is a small, woody shrub native to southeastern Russia, northern China, Korea, and Japan. Although Eleutherococcus senticosus is not related to true ginseng (Panax ginseng), the name Siberian ginseng became popular because the two plants shared some similar properties.
03-01-2012 With the growing popularity of red yeast rice (RYR) as a lipid-lowering agent, it is important to ensure that this dietary supplement is safe and effective. The objective of this review was to provide current evidence-based guidance on the use of RYR. PubMed was searched for RYR studies published 2009–2011. The review confirmed that RYR is safe and efficacious for dyslipidemia and has other potential cardioprotective applications.
02-01-2012 Fever in children is one of the most common reasons that parents and caregivers seek the advice of healthcare practitioners. As an adaptive immune response against infectious agents, fevers are a beneficial process and a positive indicator of healthy immune function. Because of the risk of serious bacterial illness, it is of utmost importance that naturopathic physicians working with the pediatric population have clear guidelines for treating and referring their pediatric patients.
02-01-2012 Anxiety is a common complaint and may range from every day stress to clinically relevant symptoms requiring medical intervention. Patients with generalized anxiety disorder (GAD) can experience excessive anxiety and worry associated with the stresses of everyday life.
12-01-2011 Vitamin E has been proposed for the prevention or treatment of numerous health conditions, often based on its antioxidant properties. Ongoing research is investigating its use in numerous diseases, particularly in cancer and heart disease. Concerns have been raised about the safety of vitamin E supplementation, particularly in high doses. Evidence suggests that regular use of high-dose vitamin E supplements may increase the risk of death from all causes by a small amount, although human research is conflicting.
12-01-2011 Research now suggests that regular aspirin use protects against breast cancer, possibly lowering risk of development and, more significantly, preventing disease recurrence. Study data from Holmes et al have shown a clinically significant protective effect against breast cancer recurrence to the degree that recommendations to take aspirin may become more common despite some inconsistencies in past research. Potential risks vs. possible benefits should now be considered in women at high risk for primary breast cancer, and especially in those women at risk of recurrence.
11-01-2011 The protective effects of omega 3 fatty acids found in fish and fish oil supplementation on cardiovascular risks and diseases has been a topic of robust research for the past 30 plus years. This paper cites select research to review trials in coronary heart disease, atherosclerosis, arrhythmias, hypertension, heart failure, and dyslipidemia to encourage among clinicians and consumers a more specific utilization of dietary advice and fish oil supplementation.
11-01-2011 Vitamin B12 is an essential water-soluble vitamin that is commonly found in a variety of foods, such as fish, shellfish, meat, eggs, and dairy products. B12 plays an important role in supplying essential methyl groups for protein and DNA synthesis.
10-01-2011 5-HTP is the precursor of the neurotransmitter serotonin. Commercially available 5-HTP is obtained from the seeds of the plant <i>Griffonia simplicifolia</i>. 5-HTP has been suggested as a treatment for many conditions. This monograph summarizes the research on the 5-HTP, including information on its most and least effective uses.
09-01-2011 Botanical remedies have been used for centuries to treat various inflammatory conditions. This review describes some recent advances in our understanding of the actions and efficacy of 2 ancient anti-inflammatory herbs--turmeric (Curcuma longa) and frankincense (Boswellia serrata)--with modern examples of the evidence of their efficacy in osteoarthritis.
09-01-2011 Vitamin B6 (pyridoxine) is required for the synthesis of the neurotransmitters serotonin and norepinephrine and for myelin formation. This monograph summarizes the research on the vitamin, including information on its most and least effective uses.
08-01-2011 Cherries, the fruit of Prunus cerasus trees, and their juice concentrates may be clinically beneficial in various conditions, including gout, arthritis, muscle injury, diabetes and neurodegeneration. In general tart cherries contain more beneficial phytochemicals.
08-01-2011 Vitamin D is one of the most publicized nutrients today. This monograph assesses the recent research, outlines the most and least promising uses for the vitamin, and explains interactions and contraindications.
07-01-2011 Hawthorn and hibiscus have a long history of use in traditional botanical medicine in many parts of the world for their multiple health effects, but especially in relation to cardiovascular disorders. In the last 15-20 years, modern research has expanded and clarified those uses. Hawthorn research has focused on congestive heart failure, and sour tea research has focused on hypertension and dyslipidemia, with several clinical trials emerging in the last 3-4 years.
07-01-2011 Zinc is necessary for the functioning of more than 300 different enzymes and plays a vital role in a large number of biological processes. This article distills the copious research surrounding the mineral and rates its effectiveness for a variety of conditions.