Peer Reviewed Articles

Parabens and Breast Cancer

by Marianne Marchese, ND
10-01-2010 
Some research has raised concern that parabens may be associated breast cancer. Parabens have been detected in human breast tissue and have shown estrogenic properties.

Dietary Considerations in Chronic Kidney Disease

by Jenna Henderson, ND
09-01-2010 
A low-protein diet can be beneficial to a patient with chronic kidney disease (CKD), but the source of that protein is important as well. Many clinicians assume that a vegan diet is superior for kidney patients, but this may not be the case.

The Therapeutic Effects of Acetyl-L-Carnitine on Peripheral Neuropathy: A Review of the Literature

by Tina Kaczor, ND, FABNO
08-01-2010 
Conventional therapies have limited success in preventing or reversing symptoms of neuropathic pain and numbness. In the past decade there has been a surge in publications suggesting acetyl-L-carnitine (ALC) may be an effective neuroprotectant and antinociceptive for peripheral neuropathy. This review highlights the uses, doses, and proposed mechanisms of action for the therapeutic effects of ALC in patients with peripheral neuropathy.

Development of the Infant Immune Function and the Effects of Breast Milk

by Catherine Clinton, ND
08-01-2010 
There is a need for more extensive research into the development of the immune system in infants so that we have a more complete understanding of how to target and prevent immune disorders. Our current understanding points to 4 main areas in the ontogeny of the infant's immune system as potential early intervention points for the prevention of immune disorders.

Marinades Reduce Heterocyclic Amines from Primitive Food Preparation Techniques

by Jacob Schor, ND, FABNO
07-01-2010 
It is certainly possible, as these papers suggest, to significantly lower the formation of carcinogens during cooking, even while barbecuing. Incorporating specific ingredients into meat through mixing, marinades, or rubs provides accessible means to inhibit formation of HCAs.

Citicoline: A Novel Therapeutic Agent with Neuroprotective, Neuromodulatory, and Neuroregenerative Properties

by Irfan Qureshi, ND
06-01-2010 
Citicoline (cytidine diphosphocholine, CDP-choline) is a novel nutrient with a broad spectrum of benefits for conditions associated with symptoms of neurological dysfunction. An endogenous compound, citicoline is an essential intermediate in the synthesis of cell membrane phospholipids and its formation is the rate-limiting step in phosphatidylcholine synthesis. It plays several important roles in human physiology, including enhancement of structural integrity and signaling for cell membranes, support of acetylcholine synthesis, and synthesis of betaine, a methyl donor.

The Role of Cortisol in Sleep

by Bradley Bush, ND
06-01-2010 
The hypothalamic-pituitary-adrenal (HPA) axis interacts with sleep in multiple ways. This article reviews the effects of the HPA axis on sleep and the converse. The hormones secreted by the hypothalamus and anterior pituitary that interact with the adrenal cortex are discussed, with implications on sleep disturbances and insomnia. A review of the stages of sleep and sleep architecture is given, and particular attention is paid to the role of cortisol. A dysfunctional HPA and alterations in the rhythm of cortisol production is described as a basis for understanding many cases of insomnia. This abnormal cortisol production and cycling is the basis for the hypothesis and the small body of research on the use of natural therapies to regulate the HPA axis and cortisol production.

L-Carnosine's Effects on Cataract Development

by Tina Kaczor, ND, FABNO
04-01-2010 

Nutritional Protocol for the Treatment of Intestinal Permeability Defects and Related Conditions

by Corey Resnick, ND
03-01-2010 
Under healthy conditions, the intestinal mucosa permits the absorption of vital nutrients from the gut lumen while presenting a barrier against the passage of pathogenic substances into the body. Leaky gut syndrome describes a pathological increase in permeability of the intestinal mucosa that causes increased absorption of intestinally derived endotoxin, antigens, inflammatory mediators, and, in some cases, intact bacteria.

An Overview of Melatonin and Breast Cancer

by Tina Kaczor, ND, FABNO
02-01-2010 

Emotions and Health: Laughter Really Is Good Medicine

by Jacob Schor, ND, FABNO
01-01-2010 

Evaluating the Bioavailability of Isoquercetin

by Jeremy Appleton, ND
01-01-2010