Abstracts & Commmentary

Replenishing Vitamin D Deficiency Improves Lung Cancer Prognosis

by Jacob Schor, ND, FABNO
08-07-2019 
An interventional trial finds vitamin D supplements specifically benefit patients with lung cancer who were vitamin D–deficient to begin with, supporting an individualized approach to supplementation in this population.

Blueberries for Knee Osteoarthritis

by Paul Richard Saunders, PhD, ND, DHANP, CCH
08-07-2019 
Study finds that blueberries improve pain, stiffness, and gait but do not reduce biomarkers of inflammation in patients with knee osteoarthritis.

Delta Tocotrienol and Bevacizumab for Recurrent Ovarian Cancer

by Kirsten West, ND, LAc, FABNO
08-07-2019 
Randomized trial shows that tocotrienol, a member of the vitamin E family, works synergistically with bevacizumab, a monoclonal antibody, to slow progression and extend survival in women with refractory ovarian cancer.

Anaerobically Prepared Fecal Microbiota Transplant for Ulcerative Colitis

by Mark Davis, ND
08-07-2019 
Study shows patients with ulcerative colitis who receive fecal microbiota transplant (FMT) experience steroid-free remission at 8 weeks in numbers greater than placebo.

Sugar-Sweetened Beverage Consumption and Risk of Dying

by Jacob Schor, ND, FABNO
07-02-2019 
A comprehensive analysis of data from 2 large cohorts, followed for several decades, suggests that sugar-sweetened beverages are a grave public health risk.

Ultra-processed Food Consumption, Appetite, and Weight Gain

by Ronald Hoffman, MD
07-02-2019 
Sophisticated inpatient trial and several other new studies confirm the harm of ultra-processed foods.

Gardening Promotes Production of Brain-Derived Neurotrophic Factor in the Elderly

by Kurt Beil, ND, LAc, MPH
07-02-2019 
The mental health benefits of gardening have been recognized for centuries and confirmed by modern-day science, but a recent study is among the first to explore the mechanism of action using biomarker data.

Probiotics, Fecal Transplant, and the Microbiome

by Andrea McBeth, ND
07-02-2019 
A study in both human volunteers and mice shows the benefit of autologous fecal transplant for reconstitution of the microbiome following antibiotic treatment. But what about probiotics?

Physician Assurance Reduces Patient Symptoms

by Paul Richard Saunders, PhD, ND, DHANP, CCH
07-02-2019 
Study finds a brief, one-sentence assurance from a physician in response to a patients’ allergic reaction significantly reduces allergic symptoms.

Benefits of Exercise for Men on Active Surveillance

by Jacob Schor, ND, FABNO
06-05-2019 
Many studies have assessed the benefits of exercise in men with prostate cancer, but a recent study is the first to look specifically at the association of physical activity and risk of progression in men who are on active surveillance. Can vigorous exercise delay prostate cancer progression?

Air Pollution and Adolescent Psychosis

by Kelsey Asplin, ND
06-05-2019 
A population cohort study from the United Kingdom finds a significant relationship between air quality and the occurrence of psychotic events during adolescence (between the ages of 12 and 18).

Synbiotics and Pomegranate Juice for Polycystic Ovary Syndrome

by Jennifer Johnson, ND, LAc
06-05-2019 
A placebo-controlled trial compares the effects of pomegranate juice, pomegranate juice with synbiotics, and a synbiotic-only beverage on insulin parameters in women with polycystic ovary syndrome. Is the addition of pomegranate juice worth the extra sugar and calories?

Is Low-Carb the Key to Lasting Weight Loss?

by Ronald Hoffman, MD
06-05-2019 
Study comparing low-carbohydrate, moderate-carbohydrate, and high-carbohydrate diets identifies key mechanism regarding sustainable weight loss.

Should Aggression Be Added to Melatonin’s Adverse Effects?

by Catherine Darley, ND
05-22-2019 
Melatonin use among adults has nearly doubled in the last decade, but comprehensive data on adverse effects is lacking. A recent randomized controlled trial used a creative setup to explore whether or not melatonin increases aggressive tendencies, an effect that has been observed in animals.

Clock Genes and Aging in the Elderly

by Tina Kaczor, ND, FABNO
05-22-2019 
Clock genes help control circadian rhythms. Several polymorphisms of the CLOCK gene, one of the first such genes to be discovered, have been identified. Could variations in the CLOCK gene explain differences in aging quality?

Wearable Devices: Usable or Useless Information?

by John Neustadt, ND
05-22-2019 
Fitness trackers and similar technologies, a multibillion dollar industry, provide users with a plethora of information. Many collect data not just on step count or miles covered, but on physiologic measures of fitness and health such as heart rate and sleep patterns. But how reliable is the data?

Light Therapy Glasses for Depression in Teens

by Kaycie Rosen Grigel, ND
05-22-2019 
Clinical trial finds a novel mode of blue light delivery improves mood in teenagers suffering from depression.

Outdoor Light Pollution Linked to Increased Depression and Suicide Risk

by Kurt Beil, ND, LAc, MPH
05-22-2019 
Light at night (LAN), often called “light pollution,” has been identified as a public health threat. A recent study links LAN specifically to increased prevalence of depression and suicide or suicidal ideation.

Melatonin to Prevent ICU Delirium

by Kelsey Asplin, ND
05-01-2019 
Delirium is a common complication among patients in the intensive care unit, but treatment options are limited and pose additional risks. Could melatonin, a simple and nontoxic intervention, be an effective therapy for this condition?

Childhood Residential Green Space Exposure Predicts Future Risk of Psychiatric Diagnosis

by Kurt Beil, ND, LAc, MPH
05-01-2019 
Exposure to green space has been shown to improve mental health in both children and adults. A large study involving nearly 1 million people is the first to show a relationship between green space exposure during childhood and risk of mental illness in adulthood.