Abstracts & Commmentary

Obesity a Significant Comorbid Concern With Statins

by Michael T. Murray, ND
06-04-2014 
New findings indicate that increase in BMI is faster in the group of individuals taking statins as compared to non–statin users, and over time, calorie and fat intake increase in people taking statin medications.

High-Protein Diets and Longevity

by Jacob Schor, ND, FABNO
05-07-2014 
This study looked at overall and disease-specific mortality in relation to dietary protein consumption. The results suggest that low protein intake during middle age followed by moderate to high protein consumption in older adults may optimize health and longevity.

Topical Curcumin for the Prevention of Oral Mucositis in Pediatric Patients

by Kirsten West, ND, LAc, FABNO
05-07-2014 
Oral mucositis can significantly compromise a patient’s quality of life. Due to the strong need to find an effective treatment for this condition, the use of topical curcumin, as this study hints, might offer benefit to this end.

Marijuana in the Management of Diabetes

by Donald I. Abrams, MD
05-07-2014 
Data from the National Health and Nutrition Examination Survey (NHANES) of 4,657 participants found marijuana use to be associated with a decreased prevalence of diabetes mellitus. The current study further examines the NHANES data.

Effect of Ashwagandha on Tests of Cognitive and Psychomotor Performance

by Robin DiPasquale, ND
05-06-2014 
This study evaluated the effects of ashwagandha (Withania somnifera) on cognitive and psychomotor performance in healthy human participants. After 14 days of treatment with the herb, outcomes showed significantly improvement and no sedative effects.

Ashwagandha for Male Infertility

by Setareh Tais, ND
04-02-2014 
Ashwagandha has been used for thousands of years to treat hypogonadism, low libido, and male infertility. The results of this study are consistent with a prior research demonstrating that Ashwagandha improves sperm parameters in infertile men with hypogonadism.

27-Hydroxycholesterol Promotes Some Breast Cancer Growth

by Jacob Schor, ND, FABNO
04-02-2014 
A new study points to cholesterol as a contributor to estrogen+ breast cancer progression. Could these results change how integrative practitioners look at cholesterol and cholesterol-lowering medications?

Vitamin D Supplementation Potentially Helpful for Chronic Urticaria

by Gregory A. Plotnikoff, MD, MTS, FACP
04-02-2014 
Researchers recently found that high-dose vitamin D boosted the effects of drug therapy for chronic urticaria, but the study was not a home run. Other interventions should also be considered.

Job Stress and Dyslipidemia

by Ryan Bradley, ND, MPH
04-02-2014 
A recent analysis provides an important reminder to the clinician about the contribution of psychosocial stress, including job strain, to cardiovascular risk.

Environmental Toxins Increase Parkinson's Risk

by Tina Kaczor, ND, FABNO
03-01-2014 
Pesticides have been implicated in neurodegenerative diseases for decades. While association is not disputed, assumptions regarding causation require a better understanding of which pesticides are suspect and who is most susceptible to the neurotoxicity of these agents. This study seeks to answer these most practical questions.

Sugar Consumption Linked to Death From Cardiovascular Disease

by Sarah Bedell Cook, ND
03-01-2014 
Sugar consumption has increased dramatically in recent history, as has cardiovascular disease. This study seeks to determine the link between the two, and its results are clear: Consumption of added sugar increases the risk of death from CVD exponentially.

Aromatase Inhibitors May Prevent Cancer

by Ian Bier, ND, PhD, LAc
03-01-2014 
This paper is of importance for several reasons; first it may foretell a time when the standard of care suggests that women at high risk for breast cancer be prescribed anastrozole and our patients will be asking us for advice. Second, there are natural substances that have aromatase inhibitory action and data from this paper may encourage the use of these materials by certain patients.

Inducing Ovulation in Women with Polycystic Ovarian Syndrome

by Jaclyn Chasse, ND
02-17-2014 
One hundred twenty patients with polycystic ovarian syndrome (PCOS) and 14-16 months of infertility were studied in this randomized, controlled clinical trial. In the study, fifty percent of the patients who received metformin restored spontaneous ovulation, and 18.3% of these achieved pregnancy.

American Ginseng Improves Cancer-related Fatigue

by Michael Traub, ND, DHANP, FABNO
02-13-2014 
In this 8-week multisite, randomized, double-blind, placebo-controlled study using 1000 mg twice daily of Panax quinquefolius (American ginseng) vs placebo in cancer patients with cancer-related fatigue, fatigue symptoms, secondary outcomes, and toxicities were assessed. At the end of the trial, the group receiving ginseng demonstrated significant improvement in fatigue with greater benefit reported in patients receiving active treatment than those who had completed treatment.

Flaxseeds Reduce Prostate Cancer Aggressiveness

by Tina Kaczor, ND, FABNO
02-13-2014 
This small study reminds us that cancerous growth, no matter what stage, is dynamic and may be influenced by lifestyle choices.

Leaky Gut and Chemo

by Jacob Schor, ND, FABNO
02-13-2014 
Traditionally, one of the goals of naturopathic support for people undergoing chemo has been to help prevent diarrhea and leaky gut. But this study suggests such tactics may actually be working against the chemotherapy.

New Evidence Suggests Chemoprevention Activity of Green Tea Supplements

by Lise Alschuler, ND, FABNO
02-13-2014 
In a presurgical trial of postmenopausal female breast cancer patients comparing green tea capsule supplementation to no green tea supplementation, it was found that patients who consumed green tea supplements experienced a decrease in Ki-67 activity in benign cells and malignant cells compared to patients in the control group.

Pelargonium Sidoides for Pediatric Bronchitis

by Jaclyn Chasse, ND
02-06-2014 
Patients aged 1–18 were included if they were diagnosed with acute bronchitis, symptoms started less than 48 hours before the inclusion in the study, and their BSS score was ≥5 at the time of screening. Exclusion criteria included concomitant medication that could impair study results, allergic asthma, chronic obstructive pulmonary disease (COPD), bleeding disorders, immunosuppression, and chronic disease of the heart, liver, or kidney.

Vitamin E in the Treatment of Alzheimer's Disease

by Sarah Bedell Cook, ND
02-01-2014 
Vitamin E is of interest in the treatment of Alzheimer's disease (AD) because of its antioxidant properties. It has been proposed that oxidative stress underlies cognitive decline, and it is well established that vitamin E is a lipid-soluble antioxidant particularly effective at protecting cell membranes and nerve tissue. This study looked specifically at the use of vitamin E in Alzheimer's disease.

Resveratrol in Diabetes Care

by Heather Hausenblas, PhD
02-01-2014 
Using a randomized double-blind placebo-controlled clinical trial, this study examined the effects of resveratrol in lowering blood glucose and other related outcomes (eg, insulin, metabolic markers, cardiovascular risk factors) in patients with type 2 diabetes.