Abstracts & Commmentary
10-01-2013 In breast cancer survivors, women who had both central obesity and insulin resistance were more likely to have poor metabolic profiles including dyslipidemia, low-grade inflammation, and glucose dysregulation. Participants who were centrally obese but not insulin resistant had similar metabolic profiles to the lean participants in this study.
10-01-2013 The use of antioxidant supplements was associated with a 16% decreased risk of death from any cause. Vitamin C alone was associated with decreased risk of death from any cause. Vitamin E was associated with a decreased risk of recurrence.
10-01-2013 Berries provide significant amounts of polyphenols that are linked to a wide array of health benefits. Yet patients, particularly those with blood sugar problems, are often resistant to our suggestions to eat berries in quantity or with frequency out of fear of the fructose the berries contain. These studies provide the data to respond to this concern.
10-01-2013 Seven subjects showed a clinical response at 1 week, of whom 6 maintained a clinical response at 1 month. Three of the responders achieved clinical remission at 1 week and also maintained remission at 1 month.
09-01-2013 Nut consumption was associated with a significantly reduced risk of all-cause mortality. Compared to non-consumers, subjects consuming nuts >3 servings/week had a 39% lower mortality risk. A similar protective effect against cardiovascular and cancer mortality was observed.
09-01-2013 The theory that estrogen metabolite ratios are predictive of cancer risk is failing in these studies to be predictive. This current paper is one more in a series that call this hypothesis into question. It may be time for our profession to reassess the theory and rethink the clinical practices we have adopted based on these assumptions.
09-01-2013 With 1 in 3 Americans having high blood pressure, antihypertensive drugs are among the most frequently prescribed medicines in America. There are 11 different antihypertensive drug classes to choose from, each with its own risks and side effects. For those requiring a medication for control, this study suggests there may be an associated risk of breast cancer in postmenopausal women taking calcium channel blockers for a long duration.
08-01-2013 Compared with men in the lowest quartile of total long-chain omega-3 fatty acids, men in the highest quartile had a 44% increased risk for low-grade prostate cancer, a 71% increased risk for high-grade prostate cancer, and a 43% increased risk for all grades of prostate cancer.
08-01-2013 At the end of the 6-week intervention, the men in the resveratrol group had a significant decrease in tumor necrosis factor-α and interleukin 6 compared to the placebo control group.
08-01-2013 Replacing 10% of energy intake from carbohydrates with vegetable fat was associated with a 29% lower risk of lethal prostate cancer and 26% lower all-cause mortality.
08-01-2013 After the 8-week myo-inositol treatment, there was a significant reduction in LH/FSH ratio, FSH, prolactin, androstenedione, testosterone, insulin, and BMI compared to baseline; there was also a significant increase in the glucose/insulin ratio.
08-01-2013 Comparing placebo versus the B-vitamin complex intervention, the group receiving the B-vitamin complex demonstrated significant reduction of overall brain atrophy. When looking at just the placebo group, those with homocysteine levels above the median had greater gray matter atrophy than those with homocysteine levels below the median.
07-01-2013 Statins can reduce risk of dying of breast cancer more than other adjuvant therapies in use. Statins do come with risks, but they seem to be of smaller magnitude than the cancer therapies currently considered routine. If we weigh risk versus benefit, the scale is starting to tip toward statins.
07-01-2013 Modern in vitro and in vivo research provides validation of saffron as a potential medicinal plant, with studies indicating saffron has possible anticarcinogenic, antimutagenic, antioxidant, antidepressant, and memory-enhancing properties.
07-01-2013 Parents reported improvement in sleep difficulties, sleep onset delay, sleep duration, and sleep total. Parents also reported improvement of affect, attention deficit/hyperactivitiy disorder (ADHD) behaviors, repetitive behaviors, and compulsive behaviors. Parenting Stress Index improved.
07-01-2013 Infants who were introduced to fish between 6 and 12 months had a statistically significant lower incidence of wheezing at 48 months when compared to infants who were not introduced to fish in the first year of life. Infants who were introduced to fish between 0 and 6 months had slightly higher risk of wheezing at 48 months. The consumption of less than 1/2 serving per week of fatty fish was associated with a significantly higher incidence of wheezing at 48 months.
07-01-2013 After 8 weeks, participants consuming the high and intermediate flavanol cocoa products did significantly better on both trail-making tests; had significantly better verbal fluency scores; and had significantly reduced insulin resistance, blood pressure, blood glucose, and levels of lipid peroxidation. None of these test results changed in participants who consumed the low-flavanol cocoa.
06-01-2013 This was an 8-week pilot study of daily yogic meditation versus relaxation in mildly depressed, elderly caregivers of dementia patients. The intervention group practiced Kundalini yoga with Kirtan Kriya meditation for 12 minutes daily; the placebo group listened to a prescribed relaxation CD for the same length of time. Measures of depression, mental health, cognitive function, and telomerase activity were assessed.