Abstracts & Commmentary

Low Fat Diet and Telomere Length in Prostate Cancer Patients

by Ian Bier, ND, PhD, LAc
11-01-2013 

Reducing Risk of Breast Cancer Recurrence by Focusing on Metabolic Parameters

by Lise Alschuler, ND, FABNO
10-01-2013 
In breast cancer survivors, women who had both central obesity and insulin resistance were more likely to have poor metabolic profiles including dyslipidemia, low-grade inflammation, and glucose dysregulation. Participants who were centrally obese but not insulin resistant had similar metabolic profiles to the lean participants in this study.

Supplement Use After Breast Cancer

by Tina Kaczor, ND, FABNO
10-01-2013 
The use of antioxidant supplements was associated with a 16% decreased risk of death from any cause. Vitamin C alone was associated with decreased risk of death from any cause. Vitamin E was associated with a decreased risk of recurrence.

Berries Improve Glycemic Response to Bread or Sugar

by Jacob Schor, ND, FABNO
10-01-2013 
Berries provide significant amounts of polyphenols that are linked to a wide array of health benefits. Yet patients, particularly those with blood sugar problems, are often resistant to our suggestions to eat berries in quantity or with frequency out of fear of the fructose the berries contain. These studies provide the data to respond to this concern.

Fecal Transplants in Ulcerative Colitis

by Mark Davis, ND
10-01-2013 
Seven subjects showed a clinical response at 1 week, of whom 6 maintained a clinical response at 1 month. Three of the responders achieved clinical remission at 1 week and also maintained remission at 1 month.

Eating Walnuts Extends Longevity

by Mona Morstein, ND
09-01-2013 
Nut consumption was associated with a significantly reduced risk of all-cause mortality. Compared to non-consumers, subjects consuming nuts >3 servings/week had a 39% lower mortality risk. A similar protective effect against cardiovascular and cancer mortality was observed.

The Problem With Estrogen Metabolite Ratios

by Jacob Schor, ND, FABNO
09-01-2013 
The theory that estrogen metabolite ratios are predictive of cancer risk is failing in these studies to be predictive. This current paper is one more in a series that call this hypothesis into question. It may be time for our profession to reassess the theory and rethink the clinical practices we have adopted based on these assumptions.

Calcium Channel Blocker Use and Breast Cancer Risk

by Tina Kaczor, ND, FABNO
09-01-2013 
With 1 in 3 Americans having high blood pressure, antihypertensive drugs are among the most frequently prescribed medicines in America. There are 11 different antihypertensive drug classes to choose from, each with its own risks and side effects. For those requiring a medication for control, this study suggests there may be an associated risk of breast cancer in postmenopausal women taking calcium channel blockers for a long duration.

Do Fatty Acids Really Increase Risk of Prostate Cancer?

by Douglas MacKay, ND
08-01-2013 
Compared with men in the lowest quartile of total long-chain omega-3 fatty acids, men in the highest quartile had a 44% increased risk for low-grade prostate cancer, a 71% increased risk for high-grade prostate cancer, and a 43% increased risk for all grades of prostate cancer.

Resveratrol Decreases Inflammation

by Heather Hausenblas, PhD
08-01-2013 
At the end of the 6-week intervention, the men in the resveratrol group had a significant decrease in tumor necrosis factor-α and interleukin 6 compared to the placebo control group.

Vegetable Intake and Prostate Cancer Mortality

by Jacob Schor, ND, FABNO
08-01-2013 
Replacing 10% of energy intake from carbohydrates with vegetable fat was associated with a 29% lower risk of lethal prostate cancer and 26% lower all-cause mortality.

Myo-Inositol in Polycystic Ovarian Syndrome

by Setareh Tais, ND
08-01-2013 
After the 8-week myo-inositol treatment, there was a significant reduction in LH/FSH ratio, FSH, prolactin, androstenedione, testosterone, insulin, and BMI compared to baseline; there was also a significant increase in the glucose/insulin ratio.

Will B Vitamins Prevent Alzheimer's Disease?

by Benjamin Lynch, ND
08-01-2013 
Comparing placebo versus the B-vitamin complex intervention, the group receiving the B-vitamin complex demonstrated significant reduction of overall brain atrophy. When looking at just the placebo group, those with homocysteine levels above the median had greater gray matter atrophy than those with homocysteine levels below the median.

Statins may reduce cancer related mortality

by Jacob Schor, ND, FABNO
07-01-2013 
Statins can reduce risk of dying of breast cancer more than other adjuvant therapies in use. Statins do come with risks, but they seem to be of smaller magnitude than the cancer therapies currently considered routine. If we weigh risk versus benefit, the scale is starting to tip toward statins.

Saffron Improves Sexual Dysfunction

by Heather Hausenblas, PhD
07-01-2013 
Modern in vitro and in vivo research provides validation of saffron as a potential medicinal plant, with studies indicating saffron has possible anticarcinogenic, antimutagenic, antioxidant, antidepressant, and memory-enhancing properties.

Melatonin Supplementation Improves Sleep in Children with Autism Spectrum Disorder

by Jessica Mitchell, ND
07-01-2013 
Parents reported improvement in sleep difficulties, sleep onset delay, sleep duration, and sleep total. Parents also reported improvement of affect, attention deficit/hyperactivitiy disorder (ADHD) behaviors, repetitive behaviors, and compulsive behaviors. Parenting Stress Index improved.

Baby's First Taste of Fish: Optimal Timing Prevents Asthma

by Setareh Tais, ND
07-01-2013 
Infants who were introduced to fish between 6 and 12 months had a statistically significant lower incidence of wheezing at 48 months when compared to infants who were not introduced to fish in the first year of life. Infants who were introduced to fish between 0 and 6 months had slightly higher risk of wheezing at 48 months. The consumption of less than 1/2 serving per week of fatty fish was associated with a significantly higher incidence of wheezing at 48 months.

Chocolate May Improve Cognitive Function

by Jacob Schor, ND, FABNO
07-01-2013 
After 8 weeks, participants consuming the high and intermediate flavanol cocoa products did significantly better on both trail-making tests; had significantly better verbal fluency scores; and had significantly reduced insulin resistance, blood pressure, blood glucose, and levels of lipid peroxidation. None of these test results changed in participants who consumed the low-flavanol cocoa.

Meditation Increases Telomerase Activity and Improves Mental Health

by Tina Kaczor, ND, FABNO
06-01-2013 
This was an 8-week pilot study of daily yogic meditation versus relaxation in mildly depressed, elderly caregivers of dementia patients. The intervention group practiced Kundalini yoga with Kirtan Kriya meditation for 12 minutes daily; the placebo group listened to a prescribed relaxation CD for the same length of time. Measures of depression, mental health, cognitive function, and telomerase activity were assessed.