Abstracts & Commmentary

Creatine as a Natural Adjunct to Depression Treatment

by Peter Bongiorno, ND, LAc
11-01-2012 
A randomized, double-blind placebo-controlled trial of women with major depressive disorder showed that creatine enhanced the effect of a selective serotonin reuptake inhibitor.

High Lead Levels Increase Risk of Gout

by Walter Crinnion, ND
11-01-2012 
Data from 6,153 US residents over the age of 40 were used in the study to look for an association between blood lead levels and gout attacks. The researchers tracked of the amount of purine-containing foods participants consumed. The study accounted for confounding factors that might affect gout risk.

High Fructose Corn Syrup and Pancreatic Cancer

by Lena Suhaila, ND
10-01-2012 
A systemic review and meta analysis of 10 cohort studies reveals that a diet high in fructose is associated with an increase in the risk of pancreatic cancer. However, no statistically significant association was found between intakes of total carbohydrates, sucrose glycemic index, or glycemic load and pancreatic cancer.

Frequent Chocolate Consumption May Lower BMI

by Jacob Schor, ND, FABNO
10-01-2012 
Previous studies have linked chocolate consumption with decreased risk of cardiovascular disease, but patients are still hesitant to increase consumption for fear of weight gain. This study will put those fears to rest.

Type 2 Diabetes, Depression, and Magnesium

by Carolyn Dean, MD, ND
10-01-2012 
This cross-sectional study observed 210 type 2 diabetes patients aged 65 years and above. Patients were interviewed on lifestyle and 24-hour dietary recall. Assessment of depression was based on DSM-IV criteria.

The Effects of Meditation and Exercise on Acute Respiratory Infections

by Setareh Tais, ND
10-01-2012 
In a study that included 149 healthy adults over 50 years of age, researchers compared the effects of mindfulness meditation and moderate-intensity exercise on incidence, duration, and severity of acute respiratory infections.

25-Hydroxyvitamin D Levels and Mortality

by Alan R. Gaby, MD
10-01-2012 
247,574 individuals of all ages from Copenhagen, Denmark, whose serum 25-hydroxyvitamin D level had been measured by their general practitioner between April 2004 and January 2010 participated in a retrospective observational study to find out if there is an association between serum 25-hydroxyvitamin D levels and all-cause mortality.

Vitamin D Levels and Mortality in Metabolic Syndrome

by Gregory A. Plotnikoff, MD, MTS, FACP
10-01-2012 
In a prospective cohort study, researchers tracked vitamin D levels in 1,801 white people in southwest Germany with metabolic syndrome who underwent elective coronary angiography between 1997 and 2000.

N-Acetylcysteine in the Treatment of Childhood Autism

by Kaycie Rosen Grigel, ND
09-01-2012 
Some models are now indicating that the expression of ASD traits are associated with glutamate receptor dysregulation, rather than absolute glutamate levels.

Omega-3 Fatty Acid and Epilepsy

by Barry W. Ritz, PhD
09-01-2012 
Patients had experienced at least 2 refractory focal seizures per month in the 3 months prior to the study and were on between 1 and 4 antiepileptic drugs (AEDs). Patients were excluded if their diet included oily fish (>1 meal/week) or omega-3 fatty acid supplements. Patients were administered 1,000 mg of EPA daily for 12 weeks, in concurrence with their existing AED treatment, and recorded seizure activity throughout the study.

The Complex Health Effects of Coffee

by Petra Eichelsdoerfer, ND, CN, RPh
09-01-2012 
In longitudinal cohort study, 440,260 participants were followed for 14 years to measure the effects and outcomes of drinking coffee.

Ubiquinol for Idiopathic Male Factor Infertility

by Setareh Tais, ND
09-01-2012 
In a double-blind, placebo-controlled, randomized study, 114 healthy men with primary, idiopathic male infertility were given 200 mg ubiquinol per day for 26 weeks, while the other 114 men who participated received a placebo to find out if there would be any changes in sperm concentration.

Red Wine Polyphenols' Effects on Gut Microbiota Ecology

by Barry W. Ritz, PhD
08-01-2012 
Following an initial 15-day washout period in which subjects consumed no alcohol, participants were assigned to consume either red wine (272 mL/d), de-alcoholized red wine (272 mL/d), or gin (100 mL/d), for a period of 20 days. Dose was portioned for equivalence in ethanol content for red wine and gin, and comparable total phenols in red wine and de-alcoholized red wine.

Acupuncture Improves COPD Symptoms

by Winston Cardwell, ND, LAc
08-01-2012 
One half of 68 participants with chronic obstructive pulmonary disease received “real acupuncture," while the other half received “sham acupuncture," over a 12 week period to measure how well participants tolerated the 6 Minute Walk Test (6MWT) in regards to severity of dyspnea on exertion (DOE).

Benefits of Melatonin in Solid Tumors When Used Concurrently With Chemotherapy

by Renee Lang, ND, FABNO
08-01-2012 
In 8 randomized controlled trials, a control group receiving standard chemo/radiotherapy was compared to an intervention group receiving the same treatment with the addition of melatonin to find out if melatonin affects tumor remission, overall survival, and mitigation of treatment side effects.

Metformin Reduces Cancer Mortality in Diabetics

by Jacob Schor, ND, FABNO
08-01-2012 
Starting in 1995, the University Hospital Clinic in Turin, Italy collected data on 3,685 patients treated for type-2 diabetes for comparison with the general population of the city. The patients were followed for 4.5 years to find out which diabetic medications had the lowest risk of causing cancer.

Supplemental Vitamin A May Reduce Risk of Melanoma

by Tina Kaczor, ND, FABNO
08-01-2012 
69,635 men and women aged 50-76 residing in Western Washington participated in a prospective study to find out if Vitamin A reduces the risk of melanoma.

Metformin Improves Ovarian Cancer Survival

by Katherine Neubauer, ND, FABNO
08-01-2012 
A study comparing survival times among 341 epithelial ovarian cancer patients of whom 297 were non-diabetic, 28 were type II diabetics who did not use metformin, and 16 were type II diabetics who used metformin to find out if metformin use is associated with significantly longer progression free survival and overall survival in ovarian cancer patients.

Half of Preschoolers Do Not Go Outside to Play Daily

by Matthew Baral, ND
07-01-2012 
On average, one half of the preschoolers in the 8,950 children sampled, representing 4 million children, are not being taken outside to play daily by a parent. Fifty-one percent of children were reported to go outside to play at least once per day with a parent; 58% of children not in childcare went outside daily.

Fish Oil and Cardiovascular Disease

by Keri Marshall, ND
07-01-2012 
This study concluded that based on the 14 studies analyzed, supplementation with omega-3 fatty acids did not reduce the risk of overall cardiovascular events, all-cause mortality, sudden cardiac death, myocardial infarction, congestive heart failure, or transient ischemic attack and stroke. A small reduction in cardiovascular death was found but disappeared when data from one study "with major methodological problems" was excluded.