Abstracts & Commmentary
06-01-2011 Levels of DHA were higher among high-grade cases compared with controls. Levels of TFA 18:1 and 18:2 were significantly lower among high-grade cases compared with controls. There were no other significant differences in the remaining phospholipids between control and cancer groups.
Probiotic bacteria lactobacillus acidophilus NCFM and bifidobacterium lactis Bi-07 in functional bowel disorders
06-01-2011 The combination of L-NCFM and B-LBi07 probiotic strains at 1x1011 CFU BID effectively manipulates the microbiota in subjects with FBDs and may provide a clinical benefit by reducing the severity of bloating symptoms in patients diagnosed with non-constipation IBS, functional diarrhea, or functional bloating.
05-01-2011 Previous studies in vitro and in vivo have shown omega-3 fatty acids may increase the cytotoxicity of chemotherapy agents. While such preliminary evidence points to potentiation of chemotherapy, there is little clinical trial data to date to substantiate these claims. The current abstract strengthens the body of evidence that suggests EPA/DHA may sensitize cancer cells to the cytotoxic effects of chemotherapeutics.
05-01-2011 Kefir significantly improved triple antibiotic therapy eradication of <i>H. pylori</i>. Infection was eradicated in more than three-quarters of those patients drinking kefir, compared with only half of those who received antibiotics plus placebo.
05-01-2011 Levels of DHA were higher among high-grade cases compared with controls. Levels of TFA 18:1 and 18:2 were significantly lower among high-grade cases compared with controls. There were no other significant differences of the remaining phospholipids between control and cancer groups. EPA was not associated with risk of high-grade PCa, and associations were similar for EPA+DHA to that of DHA alone.
05-01-2011 Prunes work. That is, prunes appear to do exactly what everyone has always thought they do; they act as a mild laxative. Although some would think this action is obvious, this study by Attaluri et al may be among the first human clinical trial published in the peer reviewed literature that demonstrates prune efficacy.
05-01-2011 The article reported the overall average of the baseline and post treatment nitric oxide levels; the individual results of each of the 23 participants were not included. The cranial therapy was associated with changes in NO levels in exhaled breath.
04-01-2011 Colicky infants taking L. reuteri experienced a significant decrease in daily crying time. Stool microbiology revealed an increase in lactobacilli and decrease in Escherichia coli in the treatment group. L. reuteri was well tolerated and no adverse effects were noted.
04-01-2011 Forty-two men, aged 45 to 70 years (mean age 63 (SD 5.5) years), participated in this study. All subjects entering the study had lower urinary tract symptoms (LUTS), elevated PSA and/or BHP (BPH). Other inclusion criteria were histological findings of acute or chronic non-bacterial prostatitis, normal urinary sediment and negative bacterial cultivation of urine. The diagnosis was asymptomatic inflammatory prostatitis category IV according to the National Institute of Health classification system.
04-01-2011 Ten patients undergoing "fecal bacteriotherapy," or what in the United States is often termed "fecal transplantation." In this process the bowel is cleansed with antibiotics and then fecal suspensions from healthy donors are administered daily.
04-01-2011 One hundred twenty patients with polycystic ovarian syndrome (PCOS) and 14-16 months of infertility were studied in this randomized, controlled clinical trial. Patients were randomly assigned to receive either 1,500 mg/day metformin or 4 grams of myo-inositol plus 400 mcg folic acid daily. In patients where in whom pregnancy occurred, patients underwent ovulation induction with recombinant follicle stimulating hormone (r-FSH) (37.5 units/day) for a maximum of 3 attempts.
04-01-2011 Psorinum 6X was administered, up to 0.02 ml/Kg body weight orally once daily for all participants. Conventional (eg, infection and pain control, electrolyte balancing, abdominal/pleural paracentesis) and homeopathic (ie, administration of homeopathic medicines on pathological indications) supportive measures were also administered. Complete tumor response occurred in 33.33% of those diagnosed with stage III disease and 10.71% of those with stage IV. Partial response occurred in 41.03% and 33.93% respectively. Five-year survival rates were 38.64% (pancreatic), 38.1% (gastric), 37.5% (gallbladder), and 43.75% (liver).
03-01-2011 Controlled clinical trial to evaluate the effect of oral magnesium therapy on ocular blood flow and visual field perimetry indices in patients with normotensive glaucoma (NTG). Blood magnesium level measurement, visual field analysis, and color Doppler imaging of the orbital vessels were done before treatment and at 1 month.
03-01-2011 Cisplatin use is limited by severe neurotoxicity. When the cumulative dose exceeds 300 mg/m2, in some reports most patients suffer significant neurological damage. Cisplatin is known to increase oxidative stress; vitamin E is an antioxidant, and current evidence suggests that the antioxidant actions of vitamin E do not interfere with the therapeutic effect of chemotherapy.
03-01-2011 This open label study included 60 type 2 diabetes mellitus patients divided into 3 groups; 18 patients received sesame oil, 20 patients took a daily dose of glibenclamide (Glyburide), and 22 took both sesame oil and glibenclamide. The patients in the sesame group were supplied with sesame oil and instructed to use about 35 grams (about 2.4 tablespoons) per day in cooking or salad preparation for 60 days. Blood samples were collected at baseline and after 60 days of the experiment for analysis.
03-01-2011 Magnesium intake by the study population was inadequate and a high percentage of individuals presented alterations in the status of this mineral.
03-01-2011 Multicenter, randomized, double-blinded, placebo-controlled phase III trial. Three hundred seventy-nine patients with unresectable stage III non-small cell lung cancer (NSCLC) were enrolled between June 5, 2000, and February 6, 2006. All patients received chemotherapy, including a platinum-based agent, and radiotherapy. Patients were randomly assigned in a 1:1 ratio to receive either 120 ml of AE-941 (Neovastat) (n=188) or an equal dose of placebo (n=191) orally twice daily.
02-01-2011 This is a randomized controlled trial of 63 patients from the Eastern Hepatobiliary Surgical Hospital, Second Military Medical University, Shanghai, China, 2004 to 2007, with postoperative gastroparesis syndrome (PGS) treated with acupuncture or metoclopramide (Reglan). Acupuncture was given to 32 patients, of whom 22 were male and 10 female.
02-01-2011 Eighty subjects with a diagnosis of PCOS. After dropouts or noncompliance, 72 women participated in the study. Group 1 (n=36) were assigned to receive SX-fraction from Maitake mushroom (MSX) containing 250 mg of dried maitake mushroom powder and 18 mg of MSX per tab at a dose of 3 tabs 3 times daily between meals. Group 2 (n=36) was assigned to receive clomiphene citrate (CC), 50 mg daily on days 5-9 of menstrual cycle.
02-01-2011 Data was collected on 201 patients 10 to 18 years of age, referred to the pediatric hypertension clinic at the University of Rochester Medical Center over a 3-year period. Subjects were assessed as either having or not having primary hypertension. Patients were considered hypertensive if either systolic or diastolic measurements were above the 95th percentile at the initial visit with subsequent confirmation by 24-hour ambulatory blood pressure monitoring, assessment by a school nurse, or home monitoring. Provider-confirmed learning disabilities (LDs) and/or formal treatment for attention deficit/hyperactivity disorder (ADHD) were assessed per parent report.