Abstracts & Commmentary

Anti-Müllerian Hormone in Polycystic Ovary Syndrome

by Megan Chmelik
10-03-2018 
Prior research has shown that anti-Müllerian hormone (AMH) is elevated in women with polycystic ovary syndrome. A fascinating study discovers that AMH levels remain elevated during pregnancy and provides evidence of effects on fetal development.

Early to Supper and Late to Bed May Lower Cancer Risk

by Jacob Schor, ND, FABNO
10-03-2018 
Benjamin Franklin famously said, “Early to bed and early to rise makes a man healthy, wealthy, and wise.” According to a new study on circadian rhythms and cancer risk, early to supper may be better health advice (the study does not address wealth and wisdom).

Nanocurcumin and Riluzole for Amyotrophic Lateral Sclerosis

by Paul Richard Saunders, PhD, ND, DHANP, CCH
09-05-2018 
Study finds that nanocurcumin is safe and may improve outcomes in patients with amyotrophic lateral sclerosis (ALS), especially in those with bulbar ALS.

Intravenous Application of Mistletoe Extract

by Miranda LaBant, ND
09-05-2018 
Mistletoe extract is a widely used natural cancer therapy, typically as an adjunct to conventional therapy, but evidence suggests its benefits and safety vary according to route of administration. A phase I study set out to answer questions about the safety and tolerability of intravenously administered mistletoe.

Fructose Consumption Linked to Asthma

by Jacob Schor, ND, FABNO
09-05-2018 
The Framingham Heart Study has collected data from thousands of participants since its inception in 1948, generating a vast amount of data. A recent study used data from a subset of participants to analyze associations between fructose-containing drinks and incidence of asthma. The results give practitioners even more reason to discourage consumption of beverages such as soda and apple juice.

Greening Vacant Lots as a Cost-Effective Mental Health Intervention in Underserved Populations

by Kurt Beil, ND, LAc, MPH
09-05-2018 
Turning empty urban lots into green spaces appears to improve nearby residents’ psychological wellbeing, according to a recent study. The depression-alleviating effects are even greater among those below the poverty line.

Ketogenic Diet Improves Seizures

by Jacob Schor, ND, FABNO
08-15-2018 
Prospective clinical trial demonstrates the antiseizure effects of a ketogenic diet. Could a shift in the gut biome be responsible for the effects?

Synbiotic Supplementation for Polycystic Ovary Syndrome

by Megan Chmelik
08-15-2018 
Polycystic ovary syndrome (PCOS) has been associated with dysbiosis of the gut microbiome. Results from a recent trial suggest that synbiotic supplementation may improve glycemic control and moderate lipid levels, which could reduce diabetes and cardiovascular risks in women with PCOS.

Vitamins Might Help After Heart Attacks

by Jacob Schor, ND, FABNO
08-15-2018 
A subgroup analysis of the Trial to Assess Chelation Therapy (TACT) suggests a high-dose oral multivitamin (OMV) may provide protection from cardiovascular events for some, but not all, post-MI patients.

Fiber Feeds Bacteria to Control Type 2 Diabetes Mellitus

by Mark Davis, ND
08-15-2018 
In a randomized clinical trial, participants with type 2 diabetes consuming a high-fiber diet showed better glycemic control, an expected finding. But the mechanism underlying fiber’s benefits, as suggested in the study, challenge conventional wisdom.

Breast Tissue Microbiota

by Tina Kaczor, ND, FABNO
08-13-2018 
Naturopathic practitioners have long assumed that breast tissue, conventionally assumed to be sterile, harbored bacteria. Evidence from recent studies supports the existence of a distinct breast microbiome. A new study by Hieken et al compared the breast microbiome in benign breast disease to the microbiome in cancerous breast tissue, with fascinating observations.

Epigallocatechin-3-Gallate and Facial Dysmorphology in Trisomy 21

by Paul Richard Saunders, PhD, ND, DHANP, CCH
08-01-2018 
Study finds that low-dose epigallocatechin-3-gallate (EGCG) improves facial dysmorphology associated with trisomy-21 in mouse genetic models and human subjects.

Do Cruciferous Vegetables Contribute to Endometriosis?

by Lorinda Sorensen, ND, LAc
08-01-2018 
A prospective dietary study of a large cohort of women seeks to determine the influence of fruit and vegetable consumption on risk of endometriosis. One explanation of the surprising findings supports the role of gut inflammation in the genesis of endometriosis.

High–Saturated Fat Diet Increases Endotoxemia

by Judy Fulop, ND, FABNO
07-05-2018 
Study shows that a diet high in saturated fat leads to a rise in lipopolysaccharide, an endotoxin that may contribute to a number of inflammatory conditions.

Topical Milk Thistle for Capecitabine-Induced Hand-Foot Syndrome

by Kirsten West, ND, LAc, FABNO
07-05-2018 
Capecitabine-induced hand-foot syndrome (HFS) is a potentially treatment-limiting complication of chemotherapy. Could topical milk thistle (silymarin) mitigate capecitabine’s toxicity?

Low-Carbohydrate Diet as Treatment for Type I Diabetes in Children

by Mona Morstein, ND
07-05-2018 
Impressive results from a survey conducted via a social media site for people with type 1 diabetes who follow a very low carbohydrate diet (VLCD). Can a VLCD achieve better glycemic control than conventional care?

Elevated Biotin Intake May Interfere with Laboratory Assays

by Alexander Schauss, PhD, FACN
07-05-2018 
In 2017 the US Food and Drug Administration issued a report that laboratory results from patients on high doses of biotin could be misleading due to biotin’s interaction with the assay process. A recent study set out to determine the effects of varied doses of biotin on several of the most vulnerable tests.

Egg Consumption May Lower Risk of Cardiovascular Disease

by Jacob Schor, ND, FABNO
07-02-2018 
For decades we believed eggs were not heart-healthy, then we discovered they may not be so bad. Is it possible eggs could actually do our hearts good?

Coffee Decreases Risk of Postmenopausal Breast Cancer

by Jacob Schor, ND, FABNO
06-06-2018 
Research is making it increasingly clear that coffee does not increase breast cancer risk and may offer protection against breast cancer in certain subgroups. A recent study found that the protective effects occurred with both caffeinated and decaffeinated coffee—meaning the credit must go to compounds other than caffeine.

Caffeine, Genotyping, and Athletic Performance

by Paul Richard Saunders, PhD, ND, DHANP, CCH
06-06-2018 
A recent study compared caffeine to placebo in elite male athletes and finds caffeine’s effects on athletic performance vary by CYP1A2 genotype, which influences caffeine metabolism.